The Science of Mind-Body Transformation

The practice of mindfulness and other mind-body exercises are a scientifically proven way of restoring our mental, bodily and emotional balance (*references in the footnote).

Both medical science and cognitive-behavioral therapies endorse the practice of mindfulness, and there is an increasing number of clinicians that recommend the use of Mindful Science to their patients.

About Us

Over the past 10 years we have provided mindfulness and mind-body training to individuals and organizations, along with professional coaching to all our clients.

We integrate the use of biometrics to monitor the psychophysiological changes that occurr while practicing,

Our team has an extensive background in mind-body science, biofeedback technologies, data analysis and personalized support.

Research and Benefits

Decades of research show that a huge list of diseases and conditions improve significantly thanks to the continued practice of mindfulness:

stress and anxiety, burnout, depression, insomnia, panic attacks, phobias, chronic pain and inflammation, obesity, blood pressure, premature aging, angina pectoris, fatigue, parkinson’s, diabetes mellitus, immune problems, premenstrual syndrome …

The list of demonstrated benefits has a direct impact on all areas of our life:

Physical and mental health

Emotional regulation

Clarity and mental focus

Workspace performance

Problem solving


Attention and memory


Deep sleep

Social skills

Empathy and compassion


Optimism and joy



Connection and purpose

The Mind-Body Connection


Every physical change has a direct and instantaneous impact on your mental and emotional processes.


And every mental and emotional change has a direct and instantaneous impact on your biological processes.

During times of stress, burnout and negative emotions, the body activates a “fight or flight” where our growth functions stop, our brain limits the ability to think clearly, learn, reason, make decisions, pay attention or solve problems, and our mind quickly turns to fear and threat. A vicious circle where stress and anxiety grow exponentially.

The practice of mindfulness quickly activates a Relaxation Response in our nervous system, the psychobiological growth mode that is the counterpart of the “fight or flight” mode. Our organs re-dedicate time and energy to processes such as digestion, self-healing and cell regeneration, and the brain, by not feeling threatened and anxious, reactivates all our cognitive functions.

We feel physically relaxed and mentally aware.

Heart-Brain Coherence

Mindfulness facilitates that the heart and the brain work in a synchronized way.

Brain and heart maintain a constant bidirectional communication where the heart sends more signals to the brain than it receives.

The heart has an extensive and sophisticated neural network (more than 40,000 neurons) that helps to synchronize and harmonize a multitude of organic functions. It can operate independently of the brain network to learn, remember, process information and make decisions.

The practice of mindfulness and mind-body exercises allows both systems to acquire Coherence. The coherent signals that travel from the heart to the brain reactivate all our cortical processes, improving our cognitive functions, increasing our mental focus, reducing our stress levels, and reinforcing positive feelings and emotional stability.

This coherence can be easily measured with the biofeedback technologies that we incorporate into the Mindful Science experience.

After 3 minutes of practice

We activate a Relaxation Response, the biological counterpart of stress and anxiety. The body enters a hypometabolic state where cells consume less oxygen (up to 20% less), the heart and brain acquire a state of coherence and all our psychobiological mechanisms of growth begin to be restored.


After 6 hours of accumulated practice

Brain scans show that after 6 hours of accumulated practice various structural changes begin to be visible in areas related to emotional regulation. In addition, our ability to cope with stress improves significantly, as well as our physical and mental health.

After 4 weeks of practice

After 4 weeks the telomeres, the capsules that protect the genetic material, lengthen, delaying our cellular aging and favoring our health and mind-body well-being , as shown by the studies of Nobel Prize winner Elizabeth Blackburn.

After 8 weeks of practice

8 weeks of continuous practice allow genes linked to diseases derived from stress (including the deficiency of immune responses, various types of inflammation, premature aging, thinning of the cerebral cortex, cardiovascular problems and cancer) to modify their expression.

Our Articles

In our blog we share research articles and theoretical-practical knowledge that complement your daily experience and support your personal process of mind-body transformation.


Baer R. A., Smith G. T., Hopkins J., Krietemeyer J., Toney L. “Using self-report assessment methods to explore facets of mindfulness. Assessment.” 2006;13:27–45. [PubMed]

Bass, M., Nevicka, B., & Ten Velden, F. S. (2014). “Specific Mindfulness Skills Differentially Predict Creative Performance.” Personality and Social Psychology Bulletin. 40(9):1092­1106.

Baxter, A. J., et al. “Global prevalence of anxiety disorders: a systematic review and meta-regression.” Psychological medicine 43.05 (2013): 897-910. [PubMed]

Beary JF, Benson H. “A simple psychophysiologic technique which elicits the hypometabolic changes of the relaxation response.” Psychosom Med. 1974 Mar-Apr; 36 (2): 115-20 [PubMed]

Benson-Henry Institute for Mind Body Medicine

Benson, Herbert, 1975 (2001). “The Relaxation Response”. HarperCollins. ISBN 0-380-81595-8.

Benson, Herbert y Proctor, William. 2011. “Relaxation Revolution”. Scribner. ISBN 9781439148662.

Berridge KC et al. (2011) “Building a Neuroscience of Pleasure and Well-Being.” Psychology of well-being 1.1: 1–3. [PubMed]

Blackburn, Elizabeth y Epel, Elissa. 2017. “The Telomere Effect: The New Science of Living Younger”. Grand Central Publishing.

Carson, J. W., Carson, K. M., Gil, K. M., & Baucom, D. H. (2004). “Mindfulness-based relationship enhancement.” Behavior therapy, 35(3), 471-494 [ScienceDirect]

Chang SWC, Fagan NA, Toda K, Utevsky AV, Pearson JM, Platt ML. “Neural mechanisms of social decision-making in the primate amygdala”. Published online before print December 14, 2015, doi:10.1073/pnas.1514761112. PNAS December 29, 2015 vol. 112no. 52 16012-16017 [PubMed]

Chen, K. W., Berger, C. C., Manheimer, E., Forde, D., Magidson, J., Dachman, L., & Lejuez, C. W. (2012). “Meditative therapies for reducing anxiety: A systematic review and meta‐analysis of randomized controlled trials.” Depression and anxiety, 29(7), 545-562 [PubMed]

Colzato, L., Ozturk, A. & Hommel, B. (2012). “Meditate to create: the impact of focused-attention and open-monitoring training on convergent and divergent thinking”. Front. Psychology. 3, 116. [PubMed]

Creswell, J. D., et al. “Brief mindfulness meditation training alters psychological and neuroendocrine responses to social evaluative stress.” Psychoneuroendocrinology 44 (2014): 1­12. [PubMed]

Dusek, J. A. et al. “Genomic Counter-Stress Changes Induced by the Relaxation Response.” Ed. Philip Awadalla. PLoS ONE 3.7 (2008): e2576.PMC. Web. 17 Feb. 2016.

Elliott, Stephen B. 2005. “The New Science of Breath”. Coherence Publishing.

Farb, N., Segal, Z. V., Mayberg, H., Bean, J., McKeon, D., Fatima, Z., & Anderson, A. (2007). “Attending to the present: Mindfulness meditation reveals distinct neural modes of self-reference”. Social Cognitive and Affective Neuroscience, 2, 313–322.) [PubMed]

Farb, Norman A. S., Adam K. Anderson, and Zindel V. Segal. “The Mindful Brain and Emotion Regulation in Mood Disorders.” Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie 57.2 (2012): 70–77. Print. [PubMed]

Goldin, P. & Gross, J. (2010). “Effects of mindfulness ­based stress reduction (MBSR) on emotion regulation in social anxiety disorder”. Emotion. 10, 1. 83­91. [PubMed]

Gong, H., Ni, C. X., Liu, Y. Z., Zhang, Y., Su, W. J., Lian, Y. J., … & Jiang, C. L. (2016). “Mindfulness meditation for insomnia: A meta-analysis of randomized controlled trials.” Journal of Psychosomatic Research, 89, 1-6. [PubMed]

Greenberg, J., Reiner, K. & Meiran, N. (2012). “Mind the Trap: Mindfulness Practice Reduces Cognitive Rigidity.” PLoS One, 7(5):e36206.

Hölzel, B.K., Hoge, E.A., Greve, D.N., Gard, T., Creswell, J.D., Brown, K.W., Barrett, L.F., Schwartz, C., Vaitl, D., & Lazar, S. (2013). “Neural mechanisms of symptom improvements in generalized anxiety disorder following mindfulness training”. Neuroimage: Clinical, 2, 448-458. [PubMed]

Hölzel, B. K., Carmody, J., Vangel, M., Congleton, C., Yerramsetti, S. M., Gard, T., & Lazar, S. W. (2011). “Mindfulness practice leads to increases in regional brain gray matter density”. Psychiatry Research, 191(1), 36–43. [PubMed]

HeartMath Institute.

National Health Service (UK).

National Sleep Foundation (US)

Lazar, S. W., Kerr, C. E., Wasserman, R. H., Gray, J. R., Greve, D. N., Treadway, M. T., … Fischl, B. (2005). “Meditation experience is associated with increased cortical thickness.” Neuroreport, 16(17), 1893–1897. [PubMed]

Lin IM, Tai LY, Fan SY. (2013). “Breathing at a rate of 5.5 breaths per minute with equal inhalation-to-exhalation ratio increases heart rate variability.” Int J Psychophysiol. 2014 Mar; 91 (3): 206-11. [PubMed]

Maletic, V et al. “Neurobiology of Depression: An Integrated View of Key Findings.” International Journal of Clinical Practice 61.12 (2007): 2030–2040. [PubMed]

Moraveji N., Hagiwara T. (2012). “BreathTray: Augmenting Respiration Self-Regulation without Cognitive Deficit.” Extended abstracts of ACM CHI 2012. Austin, TX. (link)

Mukamel, R, et al. “Single-neuron Responses in Humans during Execution and Observation of Actions”. Current Biology. 2010 Apr 7. [PubMed]

Nes LS, Segerstrom SC, Sephton SE. “Engagement and Arousal: Optimism’s Effects During a Brief Stressor”. Personality & social psychology bulletin 31.1 (2005): 111–120. PMC. Web. 17 Feb. 2016. [PubMed]

Ostafin, B. & Kassman, K. (2012). “Stepping out of history: Mindfulness improves insight problem solving. Consciousness and Cognition”. 21, 2. 1031 – 1036. [PubMed]

Pert, Candace. 1999. “Molecules of Emotion: The Science Behind Mind-Body Medicine”. New York: Touchstone.

Roemer, L. et al. “Mindfulness and acceptance-based behavioral therapies for anxiety disorders.” Current psychiatry reports 15.11 (2013): 1-10. [PubMed]

Rozman D, Martin H, McCraty R, Childre L (2016). “Heart Intelligence: Connecting with the Intuitive Guidance of the Heart”. Waterfront Press

Segerstrom SC. “Optimism, goal conflict, and stressor-related immune change.” J Behav Med. 2001 Oct;24(5):441-67. [PubMed]

Stapp, H; Schwartz, J. M; Beauregard, M. (2004). “The volitional influence of the mind on the brain, with special reference to emotional self-regulation”. In Beauregard, M. (Ed.).Consciousness, emotional self-regulation, and the brain, Philadelphia, PA: John Benjamins Publishing Company, Chapter 7. ISBN 90-272-5187-8

Tang, T. et al. (2010). “Short‐term meditation induces white matter changes in the anterior cingulate.” Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15649-52. doi: 10.1073/pnas.1011043107. Epub 2010 Aug 16. [PubMed]

Taren AA, Creswell JD, Gianaros PJ (2013) “Dispositional Mindfulness Co-Varies with Smaller Amygdala and Caudate Volumes in Community Adults.” PLoS ONE 8(5): e64574. doi:10.1371/journal.pone.0064574

Vlemincx, E., Taelman, J., Van Diest, I., Van den Bergh, O. (2010). “Take a deep breath: the relief effect of spontaneous and instructed sighs.” Physiol Behav. 2010 Aug 4; 101 (1): 67-73. [PubMed]

What are the Benefits of Mindfulness. APA journal. By Daphne M. Davis, PhD, and Jeffrey A. Hayes, PhD. July/August 2012, Vol 43, No. 7. Print version: page 64 (link).

Yasuma, F. et al (Feb 2004). “Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm?”. Chest 125 (2): 683-90. [PubMed]

Zeidan, F., Johnson, S. K., Diamond, B. J., David, Z., & Goolkasian, P. (2010). “Mindfulness meditation improves cognition: Evidence of brief mental training.” Consciousness and cognition, 19(2), 597-605. [PubMed]

Ziemann AE, Allen JE, Dahdaleh NS, Drebot II, Coryell MW, Wunsch AM, Lynch CM, Faraci FM, Howard MA, Welsh MJ, Wemmie JA. (2009). “The Amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.” Cell. 2009 Nov 25; 139(5):1012-21 [PubMed]

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